WEST LAFAYETTE, Ind., Oct. 23 (UPI) -- U.S. scientists have developed a
biochip that greatly increases researchers' ability to measure the
electrical activities of cells.
The biochip produced by Purdue University researchers is said to be
capable of obtaining 60 times more data in just one reading than is
possible with current technology.
"Instead of doing one experiment per day, as is often the case, this
technology is automated and capable of performing hundreds of
experiments in one day," said Marshall Porterfield, a professor of
agricultural and biological engineering who led the research team.
The device works by measuring the concentration of ions as they enter
and exit cells. The chip can record those concentrations in up to 16
living cells temporarily sealed within fluid-filled pores in the
microchip. With four electrodes per cell, the chip delivers 64
simultaneous, continuous sources of data.
Porterfield notes about 15 percent of the drugs currently in
development affect the activities of ion channels that facilitate
communication and the transfer of electrical signals from one cell to
the next.
The device is described online in the journal Sensors and Actuators and
the study is to appear in the journal's November print edition.
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Monday, October 23
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on Mon 23 Oct 2006 08:56 AM AKDT
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